Polar Fractions

Polar Fractions: A Breakthrough in Active Pharmaceutical Ingredients

Revolutionizing Cannabis Science

One of the most groundbreaking discoveries in cannabis research is the revelation that polar fractions of specific cultivars exhibit far greater efficacy than their non-polar counterparts. This scientific breakthrough challenges the traditional focus on cannabinoids and terpenes, opening a new chapter in cannabis-based pharmaceuticals.


What Are Polar Fractions?

Polar fractions are composed of flavonoids, sugars, and other plant substances, while the levels of cannabinoids and terpenes are reduced to a minimum. Unlike traditional cannabis extracts, these polar fractions harness the power of the plant’s broader chemical composition, delivering targeted therapeutic benefits without the psychoactive effects associated with cannabinoids.


Groundbreaking Scientific Findings

A pivotal part of our research, published in the Journal of Cannabis Research (Read the Study), demonstrated that the effects of cannabis-based formulations were independent of the cannabinoid profile. This discovery sent shockwaves through the cannabis industry, which has traditionally focused on the importance of cannabinoids and terpenes.


The Entourage Effect Redefined

Traditionally, the entourage effect was believed to be dictated by the ratio of cannabinoids and terpenes. However, our findings revealed that the therapeutic potential is cultivar-specific rather than dependent on specific cannabinoid ratios. Once cannabinoids were removed, the toxic effects disappeared, while the effectiveness of the formulation significantly increased. This discovery represents a paradigm shift in how we understand and utilize cannabis in medical applications.


Pharmaceutical & Industrial Applications

The water-soluble nature of polar fractions makes them ideal for a wide range of pharmaceutical formulations and health products. These fractions can serve as:

  • A base for pharmaceutical products targeting mental wellbeing, appetite management, pain relief, fertility, performance management and vitality support.

  • An addition to various wellness products without regulatory restrictions.



Regulatory Advantage & Market Potential


A key benefit of polar fractions is that they do not fall under the Opium Act, as the cannabinoids are minimized to a legal threshold. This ensures greater flexibility for global distribution and broad commercial applications without legal restrictions.


Learn More & Collaborate With Us

For more information on the availability of different polar fractions or further scientific insights, please contact us. Join us in pioneering the next generation of cannabis-based pharmaceuticals with the power of polar fractions.